8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Symphony
DepartsWed, Sep 2nd 2026
ReturnsThu, Sep 10th 2026
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
The 180-passenger American Symphony introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography acro… 
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6 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Symphony
DepartsWed, Sep 9th 2026
ReturnsTue, Sep 15th 2026
Nights6
Departing PortMemphis
Ports of CallMemphis, Cruising the Mississippi and Ohio River, Paducah, Cruising Lake Barkley and the Cumberland River, Dover, Clarksville, Nashville
The 180-passenger American Symphony introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography acro…
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14 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Sep 12th 2026
ReturnsSat, Sep 26th 2026
Nights14
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Red Wing, La Crosse, Dubuque, Davenport, Fort Madison, Hannibal, St Louis, Mississippi River, Memphis, Mississippi River, Vicksburg, Natchez, Baton Rouge, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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15 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Heritage
DepartsSat, Sep 12th 2026
ReturnsSun, Sep 27th 2026
Nights15
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Dubuque, Davenport, Cruising the River, Hannibal, Cruising the River, St Louis, Memphis, Tunica, Cruising the River, Vicksburg, Natchez, Baton Rouge, New Orleans
Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season.
From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…
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7 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Sep 26th 2026
ReturnsSat, Oct 3rd 2026
Nights7
Departing PortNew Orleans
Ports of CallNew Orleans, Oak Alley, Baton Rouge, St. Francisville, Natchez, Vicksburg, Mississippi River, Memphis
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Heritage
DepartsSat, Sep 26th 2026
ReturnsSun, Oct 4th 2026
Nights8
Departing PortNew Orleans
Ports of CallNew Orleans, Mississippi River, Oak Alley, St. Francisville, Natchez, Vicksburg, Cleveland, Memphis (2 Days)
Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season.
From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…
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Ocean View
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15 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Sep 26th 2026
ReturnsSun, Oct 11th 2026
Nights15
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Dubuque, Davenport, Cruising the River, Hannibal, Cruising the River, St Louis, Memphis, Tunica, Cruising the River, Vicksburg, Natchez, Baton Rouge, New Orleans
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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Ocean View
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Balcony
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
